Recombinant mtTFA Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-81584-50, E-AB-81584-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: mtTFA

Target Synonym: anscription factor 6-like 1; Mitochondrial transcription factor 1; mitochondrial transcription factor A; MtTF1; mtTFA; TCF 6; TCF-6; TCF6; TCF6L1; TCF6L2; TCF6L3; TFAM; TFAM; Transcription factor 6; Transcription factor 6 like 2 (mitochondrial transcription factor); Transcription factor 6 like 2; Transcription factor 6-like 2; transcription factor 6-like 3; Transcription factor A; mitochondrial; Transcription factor A; mitochondrial; Transcription factor A; mitochondrial precursor

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC-P, IF

Isotype: IgG

Clonality: Rabbit Monoclonal

Clone No.: R08-3E2

UNIProt ID: Q00059

Background: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.
TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.

Concentration: 300 μg/mL

Immunogen: A synthetic peptide of human mtTFA

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification Method: Affinity Purified

Dilution: WB 1:1000-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Calculated MW: 29kDa

Observed MW: 24kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only