Will this work with my ABS system?

Yes. This assembly is built to integrate with factory ABS sensors and wiring. Your truck's anti-lock braking remains fully functional once installed.

Do I need to replace the brake rotor or caliper at the same time?

Not necessarily. This kit addresses the wheel hub and bearing only. If your rotors or calipers show wear, address those separately—the hub swap won't force a full brake rebuild.

What hardware is in the box?

You're getting the hub and bearing assembly itself. Any fasteners or retaining hardware specific to your truck's setup should be checked against your service manual before assembly—don't assume they're included.