Integrin beta 3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11115-50, MB11115-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P05106

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 87 kDa; Observed MW: 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Integrin beta 3 in U87-MG lysates using Integrin beta 3 antibody., Western blot analysis of Integrin beta 3 in Hela lysates using Integrin beta 3 antibody.

Alternative Name: ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61

Immunogen: Recombinant protein of human Integrin beta 3

Conjugate: Unconjugated

Modification: Unmodified