PF-06869206 is an orally selective bioavailable inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with IC50 of 380 nM.

Product information

CAS Number: 2227425-05-8

Molecular Weight: 374.75

Formula: C15H14ClF3N4O2

Chemical Name: 3-chloro-7-[2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile

Smiles: CC1NC2=C(N=C(C(C#N)=C2N2CC(CO)OCC2)C(F)(F)F)C=1Cl

InChiKey: ATFQBBCQZKVZJN-UHFFFAOYSA-N

InChi: InChI=1S/C15H14ClF3N4O2/c1-7-10(16)11-12(21-7)13(23-2-3-25-8(5-23)6-24)9(4-20)14(22-11)15(17,18)19/h8,21,24H,2-3,5-6H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

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