LIM and SH3 domain protein 1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8817-50, ES8817-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],

Alternate Name: LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 38kD

Human Gene ID: 3927

Human SWISS Prot NO: Q14847

Subcellular Location: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Associated with the F-actin rich cortical cytoskeleton.

Research Use Only