Change is afoot at the No. 1 Ladies' Detective Agency when Mma Makutsi arrives with a business plan for its proprietress, as well as an outline of her new venture: the Handsome Man's De Luxe Cafe.

In the course of one turbulent day, the agency gains a dubiously qualified Assistant Detective and takes on the challenge of identifying a lady with no name and no memory. But when Mma Makutsi's entrepreneurial future comes under threat, Charlie is led astray and Violet Sephotho turns restaurant critic, only Mma Ramotswe's infallible instincts can transform disruption into a force for good.