Streptavidin SilaMag™ Magnetic Nanoparticles

Our High Capacity Streptavidin Functionalized Magnetic Nanoparticles (Streptavidin SilaMag NanoBeads) are engineered with an average particle size of 400 nm for the rapid and specific isolation of biotinylated molecules. Manufactured via a modified Stöber process by the hydrolysis of orthosilicates followed by covalent streptavidin coupling, our proprietary functionalization procedure ensures that the biotin-binding activity of the immobilized streptavidin is optimally preserved.

Key Features:

• High Binding Capacity: Extensively optimized to bind >1000 pmol of free biotin per mg of particles.
• Minimal Background: Low non-specific binding to non-targeted proteins and nucleic acids.
• Rapid Kinetics: Fast magnetic separation speeds up workflows and reduces assay times.
• Physical Properties: Uniform 400 nm silica-coated magnetic core structure.

Applications:

• Affinity purification and isolation of biotin-tagged recombinant proteins and ligands.
• Solid-phase binding assays and immunoassay development.
• Next-Generation Sequencing (NGS) library preparation and nucleic acid separation.
• Cell separation assays and antigen purification utilizing biotinylated antibodies.