After 18 years of research, Melasyl is a new patented active ingredient that fights and prevents hyperpigmentation like never before at La Roche-Posay. Melasyl acts on excess melanin before it produces spots on the skin, for depigmenting efficacy proven by clinical studies. With La Roche-Posay Mela B3 Serum 30ml after 1 week the skin tone appears more even, at 2 weeks the visibility, color and number of dark spots appear reduced.