medicube PDRN Pink Cica Soothing Toner: A PDRN-Forward Toner for Calming and Repair

medicube's PDRN Pink line is the brand's PDRN-focused range, extending Korean PDRN (polydeoxyribonucleotide) skincare beyond pure serum delivery into full routines. The Pink Cica Soothing Toner is the toner step in this routine, combining PDRN (the Korean clinical-grade salmon DNA-derived active) with centella asiatica for calming. At $28.20 for 250ml, it's priced accessibly for a PDRN product, reflecting the toner format (lower active concentration than serum).

PDRN skincare is a K-beauty category that grew out of the clinical Rejuran injection market. Topical PDRN provides some of the same collagen-boosting and skin-regenerative benefits as the injection, though at lower concentrations and without needle delivery. For users who can't access Rejuran injections or want daily PDRN maintenance at home, products like this toner provide the category at a topical level.

What It Does

PDRN binds to adenosine receptors in skin cells, upregulating collagen synthesis and supporting skin regeneration. Centella asiatica (cica) provides calming and barrier support. Hyaluronic acid adds hydration. The toner format delivers these actives as the first treatment layer in the routine, priming skin for subsequent serums and creams. The "pink" refers to the subtle tint of the PDRN complex.

Who It's For

• Post-procedure skin: Supports recovery after peels, lasers, microneedling.
• Mature skin 35+: Daily regenerative layer.
• Sensitive or reactive skin: Cica calming plus PDRN repair.
• PDRN skincare enthusiasts: Layer toner, serum, and cream in PDRN routine.
• Rejuran injection users: Between-treatment maintenance.

Key Specs

• Volume: 250ml
• Price: $28.20
• Hero actives: PDRN, centella asiatica, hyaluronic acid
• Texture: watery toner, light
• Fragrance: minimal
• Use: morning and evening after cleansing

How to Use

After cleansing, dispense toner onto palms or cotton pad, pat gently into face and neck. Allow 30 seconds absorption before layering serums. Use morning and evening. For 7-skin method: apply 3 to 7 thin layers, patting each in before the next.

For post-procedure recovery: use liberally, apply with cotton pads as compresses on reactive zones for 10 minutes.

FAQ

How does this compare to the Rejuran topical?

Rejuran's topical uses c-PDRN (converted PDRN) formulated by Pharma Research, the company that pioneered the injection. medicube's PDRN is generic-category PDRN at topical concentrations. Rejuran typically has stronger clinical pedigree; medicube is more accessible. For core PDRN authenticity: Rejuran. For accessible daily use: medicube.

Is it as effective as the injection?

No. Injections deliver high-concentration PDRN subcutaneously. Topicals deliver lower concentration through skin. Topical PDRN supports skin function but doesn't replicate injection results.

Can I use this with retinol?

Yes, and beneficially. Apply toner first, then retinol. The PDRN and cica reduce retinol-induced irritation.

Is it vegan?

PDRN is salmon DNA-derived, so products containing it are not vegan. For vegan PDRN alternatives, look for synthetic or plant-derived alternatives (less established).

How long does 250ml last?

Twice daily use: 3 to 4 months.

Related Products

Pair with medicube PDRN Pink One Day Serum for travel-size concentrated application, or build full medicube PDRN routine.

Browse the full medicube collection or related categories: PDRN skincare, Korean toners.