DNA Polymerase β Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90419-50, BS90419-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P06746(Human) Q8K409(Mouse) P06766(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat, Zebrafish

Applications: WB, IHC, IP, ICC

All Applications: WB:1:500
IHC:1:50-1:200
ICC:1:20-1:50
IP:1:10-1:20

Background: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: DNA Polymerase β polyclonal antibody detects endogenous levels of DNA Polymerase β protein.

Bioworld Molecular Weight: 38 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DNA Polymerase beta on different cell lysate using anti-DNA Polymerase beta antibody at 1/1,000 dilution.
Positive control:
Lane 1: PC-12
Lane 2: NIH-3T3
Lane 3: A431, Immunohistochemical analysis of paraffin-embedded rat lung tissue using anti-DNA Polymerase beta antibody. Counter stained with hematoxylin.

Alternative Name: POLB, DNA directed DNA polymerase beta, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, DPOLB, MGC125976, Pol B, Pol beta, POLB, Polymerase (DNA directed) beta,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified